United sit second in the table – level on points with leaders Manchester City – after a superb start to the season, winning six of their seven opening games and scoring 21 goals in the process.
But Jose Mourinho’s side are yet to face any other realistic title contenders, and Liverpool will be desperate to make a statement against the Red Devils.
Jurgen Klopp’s side have been thrilling and infuriating in equal measure, with the brilliance of Liverpool’s attack being hamstrung by a soft defence to sit seven points off the pace.
Still, form counts for little whenever United head to Anfield, and Liverpool know a win in their famous ground against Mourinho’s men will send a message to the rest of the top flight.
Liverpool host Manchester United with kick-off scheduled for 12:30pm on Saturday, October 14.
The match will be televised live on Sky Sports’ Main Event and Premier League channels, with coverage starting from 11am.
Klopp has been dealt a huge blow with the news that Sadio Mane is out for six weeks. Mane will miss this weekend’s match as well as a big clash against Tottenham, and is a doubt to face Chelsea on November 25.
Roberto Firmino was left out against the Magpies, but will likely start against United.
Midfielder Adam Lallana (thigh) is running outside again but is still several weeks from a comeback while right-back Nathaniel Clyne is also recovering well from a back injury.
Stats reveal why Klopp can be confident for Liverpool vs Man United Mourinho is still set to be without Paul Pogba after confirming that he thinks of the midfielder as a “long-term” injury problem, while Marouane Fellaini will also miss out after damaging his knee ligaments on international duty for Belgium.
Michael Carrick is out in a further midfield setback, but Romelu Lukaku has recovered.
With United lacking the height of Fellaini and Pogba, Mourinho could be tempted to play a three-man defence, bring Ander Herrera into midfield for added security before throwing on the likes of Anthony Martial to make an impact in the second half.
Liverpool starting XI: Mignolet; A.Arnold, Matip, Lovren, Moreno; Can, Henderon, Coutinho; Salah, Sturridge, Firmino
Man Utd starting XI: De Gea; Valencia, Jones, Bailly, Smalling, Blind Herrera, Matic, Mkhitaryan, Rashford, Lukaku
Head to head
Liverpool Win’s: 75
Man United Wins: 87
Match Draws: 64
Liverpool 1:1 Man United.